Bonhoeffer-van der Pol Oscillator Model of the Sino-Atrial Node: A Possible Mechanism of Heart Rate Regulation

S. Sato; S. Doi; T. Nomura

doi:10.1055/s-0038-1634966

Methods of Information in Medicine, Table of Contents

Methods Inf Med 1994; 33(01): 116-119
DOI: 10.1055/s-0038-1634966

Original Article

Schattauer GmbH

Bonhoeffer-van der Pol Oscillator Model of the Sino-Atrial Node: A Possible Mechanism of Heart Rate Regulation

S. Sato

¹Department of Biophysical Engineering, Faculty of Engineering Science Osaka University, Japan

,

S. Doi

¹Department of Biophysical Engineering, Faculty of Engineering Science Osaka University, Japan

,

T. Nomura

¹Department of Biophysical Engineering, Faculty of Engineering Science Osaka University, Japan

› Author Affiliations

Abstract

Abstract:

A Bonhoeffer-van der Pol equation with a stable limit cycle is proposed as a model of the pacemaker in the sino-atrial node to exptain heart rate regulation. Standard tools, such as the phase transition curve in nonlinear dynamic system theory, are used to analyze the model and results are compared with other studies on experiments with dogs.

Keywords

Heart Rate Regulation - Bonhoeffervan der Pol Model - Stable Limit Cycle - Phase Transition Curve

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References

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